SickKids Hospital

Toronto, Ontario


The Hospital for Sick Children (SickKids) is one the largest hospital and research facility dedicated to childhood diseases in Canada and North America.  The  SickKids Garron Family Comprehensive Cancer Centre sees over 350 primary cancer cases per year including more than 100 new brain tumor patients, and  provides consultations for brain tumor patients worldwide. The dedicated multidisciplinary Pediatric Brain Tumor team is comprised of social workers, psychologists, rehabilitation specialists, neuro-radiologists, neuro-pathologists, 5 neuro-oncologists and 5  pediatric neurosurgeons who are all also deeply engaged in innovative  clinical trials and basic/translational research on childhood brain tumors. Many team members are laboratory scientists in the Arthur and Sonia Brain Tumor Research Centre - home to the MAGIC , Rare Brain Tumor and BMMRD international collaborative consortia, and are global leaders who have led critical scientific breakthroughs to advance diagnosis, classification and treatment of more common childhood brain tumors such as medulloblastoma and low grade gliomas, as well as rare cancers including CNS rhabdoid tumors/ATRTs, ETMRs and DIPG.  Some of the current areas of research include novel therapeutic approaches for high risk infant brain tumors, cognitive enhancement/preservation therapies, immuno- and targeted therapy for brain tumors, new methods of drug delivery and cancer stem cell therapeutics.

Housing Information

Ronald McDonald House Charities Toronto
240 McCaul Street
Toronto, ON, M5T 1W5

Contact information


555 University Ave
Toronto, ON, M5G 1X8


Phone: 416-813-7457

Fax: 416-813-8024



Principal Investigator
Dr. Bouffet is a Professor of Paediatrics in the University of Toronto, Garron Family Chair in Childhood Cancer Research and Head of the Neuro-oncology Section in the Division of Haematology/Oncology at The Hospital for Sick Children (SickKids), Toronto. He graduated in 1980 from the medical school at the University of Lyon. Following graduation he trained and practiced in Lyon; he was Head of the Department of Neuro-oncology, Centre Leon Berard, during the period 1992-1995. He then moved to the United Kingdom where he was Consultant Paediatric Oncologist at the Hospital for Sick Children, Bristol (1996-1998) and the Royal Marsden Hospital, Sutton UK (1998-2000). In 2000 he was recruited to SickKids in Toronto to develop and head a multidisciplinary paediatric neuro-oncology program within the Division of Haematology/Oncology. In 1998-200, Bouffet was co-Chairman of the Brain Tumour Committee of the International Society of Pediatric Oncology (SIOP) and is currently Chair of the Canadian Paediatric Brain Tumour Consortium. He is a member of the steering committee of the brain tumour committee of the Children’s Oncology Group, and chair of the Infant Brain Tumours Committee. Bouffet is a Senior Associate Scientist in the Research Institute at SickKids. My research interests are in the area of novel treatments and clinical trials in children with brain tumours. He is author or co-author of over 400 peer-reviewed manuscripts and author/co-author on numerous book chapters in the field of neuro-oncology. He was the recipient of several awards, including the Alvin Zipursky Teaching Award, the Claus Wirsig Humanitarian Award, and the Richard Rowe Award for Clinical Excellence in Paediatric Medical Care. In 2011, he became the inaugural recipient of the Garron Family Chair in Childhood Cancer Research and is currently the President of the International Society of Paediatric Oncology (SIOP).
Co-Principal Investigator
Senior Neuro-Oncologist
Dr Huang is a neuro-oncologist in the Pediatric Brain Tumor program, senior scientist/principal investigator in the Cell Biology Program and the Arthur and Sonia Labatt Brain Tumor Research Center at the Hospital for Sick Children, and holds academic appointments as Professor of Pediatrics, Medical Biophysics, Lab Medicine and Pathobiology at the University of Toronto, Canada. Dr Huang’s clinical and research interest is in biology and innovative therapies for rare pediatric brain tumors, and brain tumors arising in infancy. She established and leads the Rare Brain Tumor Consortium (, a unique worldwide biorepository and clinical registry for rare brain tumors. Studies from her lab has helped to advance biological understanding and novel therapies for rare embryonal brain tumors including ETMRs, PNETs and ATRTs.