University of Alabama at Birmingham, Children's of Alabama

Birmingham, Alabama

Description

Since 1911, Children’s of Alabama has provided specialized medical care for ill and injured children. Ranked among the best pediatric medical centers in the nation by U.S. News & World Report, Children’s provided care for youngsters from every county in Alabama, 42 other states and seven foreign countries last year, representing more than 677,000 outpatient visits and more than 15,000 inpatient admissions. With more than 2 million square feet, it is one of the largest pediatric medical facilities in the United States. Children’s offers inpatient and outpatient services across its Russell Campus on Birmingham’s historic Southside with additional specialty services provided at Children’s South, Children’s on 3rd and in Huntsville and Montgomery. Primary care is provided at more than a dozen medical offices in communities across central Alabama. Children’s of Alabama is the only medical center in Alabama dedicated solely to the care and treatment of children. It is a private, not-for-profit medical center that serves as the primary site of the University of Alabama at Birmingham (UAB) pediatric medicine, surgery, psychiatry, research and residency programs. More information is available at childrensal.org.

Contact information

 

1600 7th Avenue South

Birmingham, AL  35233

Team

Principal Investigator
Pediatric Hematologist/Oncologist
Dr. Girish Dhall is a Professor of Pediatrics and Benjamin Russell Endowed Chair in Pediatric Hematology & Oncology, and Division Director of the Pediatric Hematology, Oncology, and Blood & Marrow Transplantation Program at the University of Birmingham in Alabama (UAB) and Children's of Alabama (COA). He is Director of the COA Pediatric Clinical Trails Office, Deputy Director of the Neurofibromatosis Clinical Trials Consortium, and he is titled Senior Scientist at UAB’s O’Neal Comprehensive Cancer Center. He is also Head of the Pediatric Neuro-oncology program. His major area of research interest is clinical research in CNS germ cell tumors and infant medulloblastoma and designing early phase clinical trials for patients with pediatric brain tumors.
Co-Principal Investigator
Pediatric Hematologist/Oncologist
Dr. Friedman is a graduate of the College of William and Mary and the Medical College of Georgia. He completed his pediatric residency and fellowship in pediatric hematology/oncology at UAB. His primary interests are pediatric neuro-oncology and conducting pediatric virotherapy and immunotherapy brain tumor research. His overarching goal is to improve outcomes for children with malignant brain tumors by developing and improving novel, targeted therapies in the lab and then translating these therapies to clinical trials. Herpes virus (HSV), which typically causes cold sores, has been engineered to be safe for normal cells but can infect and kill cancer cells and stimulate the patient’s own immune system to attack the tumor providing a one-two punch at killing tumor cells. To maximize the benefit of this therapy, his lab focuses on determining mechanisms of therapeutic resistance by exploring the role of tumor genotype, phenotype, and microenvironment; and cellular defense mechanisms so that newer viruses, novel combinations, and unique routes of virus delivery may be developed to circumvent resistance mechanisms. Dr. Friedman is the principal investigator for the first-ever pediatric trial of HSV G207 in children with recurrent or progressive brain cancers
Pediatric Hematologist/Oncologist
Pediatric Hematologist/Oncologist