Patients & Families

The Pacific Pediatric Neuro-Oncology Consortium (PNOC) was formed in 2012 to improve the overall and quality outcomes for children and young adults with central nervous systems (CNS) tumors.  Operated out of the University of California San Francisco (UCSF), since its founding PNOC has grown from 8 to more than 25 sites across the world, recently expanding to Switzerland, Australia, Israel, India, and Amsterdam.  Through their cooperative network, PNOC is fostering worldwide collaboration in the pursuit of enhanced clinical trial development and treatments for CNS cancer, the deadliest form of pediatric cancer.

Patients and families are at the core of everything that we do. To a large degree, the reason to begin this consortium was based upon the need for innovative clinical trial development that fully harnessed emerging molecular technologies on behalf of children with the highest unmet needs. Since its inception, PNOC has pushed beyond older paradigms and historic trial designs.  Our overarching goal is to conduct early-phase clinical trials, which emphasize novel, biology-driven, precision-based therapeutics.  To this end, PNOC pursues clinical strategies based on the molecular and genetic make-up of each patient’s individual tumor. We assess therapies aimed at interfering with specific cellular pathways and aspire to spare patients from therapy that is not optimized for their unique tumor type.  Collaboration with multiple scientists and clinicians across the globe, sharing information and results freely in easily accessible data networks in real time, allows us to fulfil our core mission: to improve the outcome of all of our patients.

Apr 30

Informational Webinar Series

DMG/DIPG, ATRT, and Ependymoma

You’re invited to hear directly from the PNOC experts about the current state of research and...

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Dec 04

PNOC Adds 5 new US sites

Announcement From PNOC

After a rigorous application process with 14 applications, PNOC is excited to announce we have...

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May 06

Survey for Craniopharyngioma Patients and Families

Anonymous survey to hear from you

Dear craniopharyngioma survivor families, The Pediatric Pacific Neuro-oncology...

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Clinical Trials and Research Groups

Click below to learn more about the Clinical Trials PNOC currently offers, or the different Research Groups to connect with.

Learn More About Clinical Trials Learn More About Research Groups

Find a Center Near You

PNOC partners with neuro-oncology centers across the United States and across the globe. See which center is nearest you to connect with their team.