Research Group

Advanced Practice Providers & Nurse Investigator Committee (APPNIC)

Advanced Practice Providers & Nurse Investigator Committee (APPNIC) is a sub-committee of PNOC, with voluntary membership comprised of advanced practice providers (APPs) and registered nurses (RNs) from PNOC institutions across the globe.   APPs and RNs are instrumental in carrying out the mission of PNOC and providing access to clinical trials for children with brain tumors. Our adult and pediatric colleagues have led an effort to engage nursing and nurse scientists in collaborative work within clinical trial consortiums. These groups have recognized untapped areas of research including fatigue, patient and family education, symptom management, fertility, family coping, quality of life, long-term sequelae of treatment and other areas of survivorship.  Formalizing the incorporation of an APP and nursing group creates an opportunity to enhance the work of PNOC surrounding the clinical care of children with brain tumors and the illness experience of patients and their families.   


APPNIC was created as a sub-committee within PNOC in spring 2021 in an effort to maximize efficiency and streamline processes across the institutions.  We collaborate with each PNOC protocol study team and assist with protocol development, including feasibility of study aims and calendar development.  Once a protocol is finalized, the APPNIC study team creates supportive documentation, including roadmaps, supportive care recommendations, and drug related educational sheets, specific to each protocol. Our goal is to heighten the innovative and bold advancements of PNOC protocols within the nursing profession. 


APPNIC meets virtually on the second Friday of every month at 10:30 AM to 11:30 AM PST.  If you’re interested in learning more or becoming a member, please email Carly Hoffman, PNP (