Participating Sites

PNOC is proud of the exceptional commitment and work of our sites across the United States, Canada, Europe and Australia. The teams at each of PNOC’s member hospitals are made up of specialists in different areas of pediatric brain tumor treatment – such as oncology, neurosurgery, neuropsychology and radiation therapy – who combine their expertise to optimize care for each patient. Each member institution contributes to the consortium’s goals by carrying out laboratory research, taking part in protocol design and development and treating patients on PNOC trials. 

Chicago, IL

Ann & Robert H. Lurie Children’s Hospital of Chicago, formerly Children’s Memorial Hospital, provides superior pediatric care in a setting that offers the latest benefits and innovations in medical technology, research and family-friendly design. As the largest pediatric provider in the region with a 130 year legacy of excellence, kids and their families are at the center of all we do.

Los Angeles, CA

Children’s Hospital Los Angeles (CHLA) is one of the largest children’s hospitals in the United States and offers a new state-of-the-art hospital building that opened in July, 2011. For the fifth year in a row, our hospital has been named to the prestigious National Honor Roll by U.S. News & World Report rankings. CHLA is ranked fifth in the nation for cancer care on the U.S. News & World Report Best Children's Hospitals List.

Minneapolis, MN

Children’s Minnesota is an independent and not-for-profit health care system that provides comprehensive care exclusively for children and young adults.  Children’s Minnesota has two freestanding hospitals, 12 primary and specialty-care clinics and six rehabilitation sites.   Children’s has the largest pediatric neuro-oncology program in Minnesota, and provides inclusive and collaborative care for children and young adults diagnosed with all types of CNS tumors.


Children’s National Medical Center in Washington, DC, has been serving the nation’s children since 1870. Home to Children’s Research Institute and the Sheikh Zayed Institute for Pediatric Surgical Innovation, Children’s National is consistently ranked among the top pediatric hospitals by U.S.News & World Report and the Leapfrog Group. Children’s National is a Magnet® designated hospital. With 303 beds and eight regional outpatient centers, Children’s National is the premier provider of acute pediatric services in the Washington metropolitan area.

Boston, MA

The Pediatric Brain Tumor Center at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center is a world-renowned destination for children with malignant and non-malignant brain and spinal cord tumors. Our patients receive care from neurologists, neuro-oncologists, neurosurgeons and pediatric subspecialists with extensive expertise in treating these types of childhood cancers.

Portland, Oregon

The mission of the Pediatric Neuro-Oncology Program at OHSU Doernbecher Children’s Hospital is to promote the well-being of children and adolescents with brain tumors and spinal cord tumors by ensuring excellence in patient care, education, and research. Our patients and their families are our top priority and we provide the comprehensive care that they need, with expert physicians in multiple sub-specialties as well as staff who meet the needs that go beyond the medical and surgical treatments.

Durham, NC

Established in 1930, Duke University School of Medicine is the youngest of the nation’s top medical schools. Ranked tenth among its peers, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where traditional barriers are low, interdisciplinary collaboration is embraced, and great ideas accelerate translation of fundamental scientific discoveries to improve humanhealth locally and around the globe.

Baltimore, MD

The Pediatric Neuro-Oncology (PNO) Program at Johns Hopkins is part of the Division of Pediatric Oncology within the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.  National Cancer Institute designation as a Comprehensive Cancer Center is the gold standard for cancer hospitals, and Johns Hopkins is the only one that has earned this designation in Maryland.  Care for children and young adults with brain and spinal cord tumors is coordinated through a multidisciplinary team of providers who focus their basic, translational and clinical research exclusively on pediatric brain tumo

Hackensack, NJ

Joseph M. Sanzari Children’s Hospital is a 105-bed acute care hospital located at Hackensack University Medical Center in Hackensack, NJ. The hospital provides quaternary care services for children including gene therapy for rare diseases, pediatric kidney transplantation, epilepsy surgery, and the only Blood and Marrow and Stem Cell Transplantation Program in New Jersey for children with cancer and life-threatening genetic conditions.

Columbus, OH

Nationwide Children’s Hospital is one of the nation’s largest not-for-profit freestanding pediatric health care networks providing wellness, preventive, diagnostic, treatment and rehabilitative care for infants, children and adolescents, as well as adult patients with congenital disease. The Research Institute at Nationwide Children’s is one of the Top 10 National Institutes of Health-funded freestanding pediatric research facilities.

Perth, Australia

The Department of Paediatric and Adolescent Oncology/Haematology at Perth Children’s Hospital (PCH) provides the sole state-wide service in Western Australia for the diagnosis and management of children and adolescents with cancer and blood disorders.

Utrecht, The Netherlands

More than ten years ago, a group of parents and healthcare professionals in the Netherlands started working towards one national children’s cancer center that could accelerate advances in treatment. Those efforts led to the creation of the Princess Máxima Center for pediatric oncology, which in 2018 opened its doors for all pediatric oncology patients in the Netherlands. The Princess Máxima Center is a unique center that brings together highly complex care and innovative research.

Indianapolis, IN

The Riley Hospital for Children at Indiana University Health Comprehensive Pediatric Neuro-Oncology Program is the only dedicated, multidisciplinary program serving children and young adults with brain cancer in the state of Indiana. Our multidisciplinary program provides a strong connection with neurosurgery, neuropathology, neuroradiology, radiation oncology, rehab, adult neuro-oncology, and other partners across the institution.

Seattle, WA

Seattle Children’s Cancer Center is consistently ranked among the top 10 pediatric cancer centers in the nation by U.S. News & World Report. Seattle Children’s brain tumor team is a coordinated group of board certified specialists, including pediatric neuro-oncologists, neurosurgeons, nurse practitioners, radiation oncologists, neurologists, rehabilitation medicine physicians, neuropsychologists, nutritionists, social workers, neuro-pathologists and neuro-radiologists.


Shaare Zedek is the largest multi-disciplinary medical center in Jerusalem, offering advanced services in most specialties. With a constant commitment to improve and provide our patients with the best possible care, the 1000-bed facility treats hundreds of thousands of patients per year in its 30  departments and 70 out-patient clinics.


Sheba Medical Center, Israel's largest tertiary referral hospital, a leading education facility, and the most advanced medical center in the Middle East. During the seven decades of its existence, Sheba has earned international recognition for its leadership in clinical treatment, as well as basic and applied medical research, and healthcare management.

The Medical Center has successfully combined clinical excellence and advanced research by investing in human resources, infrastructure and facilities.

Memphis, TN

St. Jude Children’s Research Hospital is leading the way the world understands, treats and defeats childhood cancer and other life-threatening diseases. It is the only National Cancer Institute-designated Comprehensive Cancer Center devoted solely to children. Treatments developed at St. Jude have helped push the overall childhood cancer survival rate from 20 percent to 80 percent since the hospital opened more than 50 years ago. St. Jude is working to increase the overall survival rate for childhood cancer to 90 percent in the next decade. St. Jude freely shares the breakthroughs it makes, and every child saved at St. Jude means doctors and scientists worldwide can use that knowledge to save thousands more children.

St. Louis, MO

Founded in 1879, St. Louis Children’s Hospital (SLCH) is at the forefront of pediatric medicine, providing care for children around the world. As the pediatric teaching hospital for Washington University School of Medicine (WUSM), SLCH offers nationally recognized programs for training and research. Nationally recognized as a Best Children’s Hospital by U.S.

Randwick, Australia

The Kids Cancer Centre (KCC) at Sydney Children’s Hospital, Randwick (SCH) has been treating children for cancer and blood disorders in NSW, Australia and the Asia-Pacific region for over 50 years.  The Early Phase Clinical Trials Centre at the KCC works with scientists, physicians, pharmaceutical companies, and international collaborators to find the most promising results in laboratory research and translate these findings to benefit children with cancer.

Houston, Texas

As the largest pediatric cancer center in Texas and one of the largest in the nation, Texas Children’s Cancer and Hematology Centers is consistently ranked by U.S. News & World Report among the top pediatric cancer centers in the United States.


Since opening its doors as the nation's first hospital devoted exclusively to the care of children, the Children's Hospital of Philadelphia has been the setting for medical discoveries, innovations and breakthroughs that have benefited children throughout the world. Children's Hospital is ranked No. 1 on the U.S.News & World Report 2013-14 Honor Roll of the nation’s Best Children’s Hospitals and No. 1 in Parents magazine’s 2013 survey of the nation’s Best Children’s Hospitals. These rankings reflect the Hospital’s steadfast commitment to providing exceptional patient care, training new generations of pediatric healthcare providers and pioneering major research initiatives.

Zurich, Switzerland

The University Children’s Hospital in Zurich is not only the largest pediatric hospital in Switzerland but also one of the leading pediatric centers in Europe.

Birmingham, Alabama

Since 1911, Children’s of Alabama has provided specialized medical care for ill and injured children. Ranked among the best pediatric medical centers in the nation by U.S. News & World Report, Children’s provided care for youngsters from every county in Alabama, 42 other states and seven foreign countries last year, representing more than 677,000 outpatient visits and more than 15,000 inpatient admissions. With more than 2 million square feet, it is one of the largest pediatric medical facilities in the United States.

San Diego, CA

The Pediatric Brain Tumor Program at Rady Children’s Hospital and University of California San Diego consists of a multidisciplinary team from the Divisions of Neurosurgery, Hematology-Oncology, Neurology, Radiation Oncology, Pathology, and Radiology. The Program has a strong translational research component that includes members from a variety of San Diego Institutions (UCSD Moores Cancer Center,Scripps Insitute, Sanford Burnham Institute) whose goal is to provide first class care in the area of pediatric neurooncology.

San Francisco, California

UCSF Benioff Children's Hospital is recognized throughout the world as a leader in health care, known for innovation, technology and compassionate care. For more than a century, UCSF has offered the highest quality medical treatment. Today, it is one of the top children's hospitals in the nation, according to a ranking by U.S. News & World Report.

Gainesville, FL

University of Florida Shands Children’s Hospital is ranked by U.S. News and World Report among the nation’s best, and our pediatric oncology program is the highest ranked program in Florida.  This recognition, combined with an overall mission to care for and support our patients and families, leads to advanced treatment with a personalized touch from our pediatric neuro-oncology team.

Ann Arbor, MI

Behind the doors of C.S. Mott Children’s Hospital there exist teams of people who change children’s lives in extraordinary ways.

This is where the Leaders and Best come together with advanced technologies and breakthrough treatments that change lives.

Salt Lake City, Utah

The University of Utah, located in Salt Lake City in the foothills of the Wasatch Mountains, is ranked as one of the top public research universities in the nation. The School of Medicine combines excellence in teaching, research, and clinical expertise, and is widely recognized for interdisciplinary research in diverse areas of leading-edge medicine, including cancer. The Huntsman Cancer Institute, including the Center for Children’s Cancer Research, is a National Cancer Institute-Designated Cancer Center and a member of the National Comprehensive Cancer Network.